diff --git a/roles/custom/matrix-synapse/defaults/main.yml b/roles/custom/matrix-synapse/defaults/main.yml
index f2a96f789..89ce3e9bd 100644
--- a/roles/custom/matrix-synapse/defaults/main.yml
+++ b/roles/custom/matrix-synapse/defaults/main.yml
@@ -439,7 +439,19 @@ matrix_synapse_container_additional_volumes: []
 # This list gets populated dynamically based on Synapse extensions that have been enabled.
 # Contains definition objects like this: `{"name": "..", "level": "DEBUG"}
 matrix_synapse_additional_loggers: "{{ matrix_synapse_additional_loggers_auto + matrix_synapse_additional_loggers_custom }}"
-matrix_synapse_additional_loggers_auto: []
+
+matrix_synapse_additional_loggers_auto:
+  # By default, we're disabling some useless (and even toxic) spammy WARNING-level logs.
+  # Related to:
+  # - https://github.com/matrix-org/synapse/issues/16208
+  # - https://github.com/matrix-org/synapse/issues/16101
+  - name: synapse.http.matrixfederationclient
+    level: CRITICAL
+  - name: synapse.federation.sender.per_destination_queue
+    level: CRITICAL
+  - name: synapse.handlers.device
+    level: CRITICAL
+
 matrix_synapse_additional_loggers_custom: []
 
 # A list of appservice config files (in-container filesystem paths).